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Oldest Human Genome- 45,000 Year Old Neanderthals Femur Bone

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Ancient bone

A thigh bone nearly 45,000 years old brings up several unanswered questions in the researchers’ minds. It compels experts to think the degree of intimation between modern man and Stone Age ancestors.

The leg bone was discovered from the banks of the Irtysh River of Siberia in 2008. A Russian artist accidently got hold of the oldest bone of the human species that passed it to a native paleontologist. After several months paleontologist l supplied it to another group in Leipzig.

It amazed researchers to know the original age of the bone. The DNA informed that the man is approximately 43,000 to 47,000 years old. Bence Viola, co-author of the study reported that the bone was so pretty fossilized.

Moreover, the bone pointed out numerous things related to the interaction of Neanderthals with Africans and other people. It indicated the time period at which modern humans and Neanderthals first matted.

The most interesting thing is that the bone contains nearly two percent of the genome of Neanderthals. The ratio is almost similar to the amount of genome found in modern Africans.

Live Science stated that Neanderthals DNA piece means that the H.sapiens started matting with Neanderthals almost 50,000 to 60,000 years ago.

However, the connection between this pre-historic species and modern man are still in the dark. Merely the human migration of Africa to Eurasia supports the relationship of the two species. Eurasia came across Neanderthals nearly 60,000 years ago. The two groups matted because of which Neanderthals DNA was transferred in the modern human being.

This report signifies that every person on this Earth has 1 or 4 percent of Neanderthals DNA in his body.

45,000 Years Old Thigh Bone Reveals Some Huge Secrets About Human-Neanderthal Sex Timings

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45000-year-old-man's-genome-sequenced

It seems no surprise that modern humans and Neanderthals interbred as most of the Eurasian population is, genetically, 1.6% to 2.1% Neanderthal. The question has long been when they did, with a wide estimate putting it between 37,000 and 86,000 years ago based on the DNA of people alive today. But the recent study revealed that modern humans and Neanderthals interbred around 50,000 to 60,000 years ago, which is close to the time of the major expansion of modern humans out of Africa and the Middle East.

The researchers examined thigh bone of a Siberian man, discovered by Nikolai Peristov, an artist and mammoth ivory collector on the left bank of the river Irtysh near the settlement of Ust’-Ishim in western Siberia in 2008. The age of the man’s bone to be is about 45,000 years old, researchers stated.

Janet Kelso, co-author of the study and a computational biologist at the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany, told Live Science, “This is the earliest directly dated modern human outside of Africa and the Middle East, and the oldest modern human [genome] to have been sequenced.”

Formerly, the researchers had proposed modern humans firstly populated Asia by traveling towards southern, coastal route that gave rise to the present-day people of Oceania, while a later, more northern migration, gave rise to mainland Asians. Kelson stated, “the researchers’ evidence for the modern human presence in Siberia 45,000 years ago specifies that the early modern humans were not just migrated to Eurasia through a southern route as previously suggested.”

The genetic analysis of the bone revealed that the it is closely related to present-day Asians and to early Europeans. “From this we conclude that the population to which the Ust’-Ishim individual belonged diverged from the ancestors of present-day Europeans and Asians before, or at around the same time as, these groups diverged from one another,” Kelso said.

The researchers believed that 45,000 years old man carried a similar level of Neanderthal ancestry as present-day Eurasians and the Neanderthal genes moved into the ancestors of this man 7,000 to 13,000 years before he lived.

Scientists Sequenced A 45000-Year-Old Man’s Genome

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45000-year-old-man's-genome-sequenced

The DNA of a 45000 year old bone of a Siberian man has been recently examined by the researchers to find out when human and Neanderthals first interbred. On record, this is an oldest genome sequence of Homo sapiens exposing a mysterious population that may once have spanned northern Asia. The study is published in the Nature journal.

The oldest human genome also revealed that the closest extinct relatives of the modern humans were the Neanderthals who lived in Europe and Asia and vanished around 40,000 years ago. The Neanderthals interbred with ancestors of modern humans when modern humans began spreading out of Africa and today 1.5 to 2.1 percent of the DNA of anyone living outside Africa is Neanderthal in origin, study reveals.

“It remains vague when interbreeding between Neanderthals and modern humans happened. But it probably ranged between 37000 to 86000 years ago,” researchers stated.

The researchers examined the bone (human left femur), discovered by Nikolai Peristov, an artist and mammoth ivory collector on the left bank of the river Irtysh near the settlement of Ust’-Ishim in western Siberia in 2008. The age of the man’s bone to be is about 45,000 years old, researchers stated.

Janet Kelso, co-author of the study and a computational biologist at the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany, told Live Science, “This is the earliest directly dated modern human outside of Africa and the Middle East, and the oldest modern human [genome] to have been sequenced.”

Formerly, the researchers had proposed modern humans firstly populated Asia by traveling towards southern, coastal route that gave rise to the present-day people of Oceania, while a later, more northern migration, gave rise to mainland Asians. Kelson stated, “the researchers’ evidence for the modern human presence in Siberia 45,000 years ago specifies that the early modern humans were not just migrated to Eurasia through a southern route as previously suggested.”

The researchers further examined the carbon and nitrogen isotopes present in the man’s bone proposes that he ate C3 plants, which rule cooler, wetter, cloudier regions such as garlic, eggplants, pears, beans and wheat as well as animals that also dined on C3 plants. Though, the study analysis reveals that he might have eaten aquatic foods like fresh water fish.

The DNA analysis of mans’s bone revealed that the he was closely related to present-day Asians and to early Europeans. “From this we conclude that the population to which the Ust’-Ishim individual belonged diverged from the ancestors of present-day Europeans and Asians before, or at around the same time as, these groups diverged from one another,” Kelso said.

The researchers believed that 45,000 years old man carried a similar level of Neanderthal ancestry as present-day Eurasians and the Neanderthal genes moved into the ancestors of this man 7,000 to 13,000 years before he lived.

The results of the study propose that modern humans and Neanderthals interbred around 50,000 to 60,000 years ago, “which is close to the time of the major expansion of modern humans out of Africa and the Middle East,” Kelso added.

45,000 Years Old DNA Narrows Down Modern Human and Neanderthals Mating Period

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Reconstruction of Genome

Thus far, the Ust’-Ishim’s thigh bone is the most ancient bone discovered.  It belongs to a boy who died somewhere in Siberia nearly 24000 years ago. However, this tiny bone revealed some significant ancient secrets.

Recently, scientists sequenced the genome of the thigh bone of the oldest man. The researchers put this bone side by side to the ancient people who lived in Europe and Asia. The group of these people was known as Neanderthals that annihilated nearly 40,000 years ago.

Fortunately, the study shed some light upon the migration pattern of the ancient people.  It provides important clues associated with the time of mating between the modern humans and Neanderthal.

It unveiled that Neanderthal and modern human came across each other almost 50,000 to 60,000 years ago. They contain nearly two percent of Neanderthal DNA which is equivalent to the proportion of modern East Asians and Europeans.

Moreover, the location of thigh bone further verified the study. This piece of bone was found from a village that was populated by both the East Asians and Europeans.

The group of researchers who belong to Max Planck Institute of Evolutionary Anthropology uncovered these significant points. The panel is struggling hard for several years to find out the remains of DNA from ancient remnant.

The study is printed in the Wednesday issue of Journal Nature.

DNA Reveals, Neanderthals & Modern Humans First Mated 50000 years ago

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Neanderthals-modern-human-mated-50000-years-ago

Recently, the researchers examined the DNA of a 45000 year old bone of a Siberian man in order to find out when human and Neanderthals first mated.

Though, the modern humans are the only humans surviving human ancestry, others once lived on Earth. The closest extinct relatives of the modern humans were the Neanderthals who lived in Europe and Asia and vanished around 40,000 years ago. According to the recent study, the Neanderthals mated with ancestors of modern humans when modern humans began spreading out of Africa and today 1.5% to 2.1% of the DNA of anyone living outside Africa is Neanderthal in origin.

The researchers said, “it remains vague when interbreeding between Neanderthals and modern humans happened. But it probably ranged between 37000 to 86000 years ago.”

In order to resolve this mystery, the researchers examined the shaft of a thighbone, which is discovered by Nikolai Peristov, an artist and mammoth ivory collector on the left bank of the river Irtysh near the settlement of Ust’-Ishim in western Siberia in 2008. The age of the man’s bone to be is about 45,000 years old, researchers stated.

Janet Kelso, co-author of the study and a computational biologist at the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany, told Live Science, “This is the earliest directly dated modern human outside of Africa and the Middle East, and the oldest modern human genome to have been sequenced.”

In the past, the researchers had proposed modern humans firstly populated Asia by traveling towards southern, coastal route that gave rise to the present-day people of Oceania, while a later, more northern migration, gave rise to mainland Asians. Kelson stated, “the researchers’ evidence for the modern human presence in Siberia 45,000 years ago specifies that the early modern humans were not just migrated to Eurasia through a southern route as previously suggested.”

The researchers further examined the carbon and nitrogen isotopes present in the man’s bone proposes that he ate C3 plants, which rule cooler, wetter, cloudier regions such as garlic, eggplants, pears, beans and wheat as well as animals that also dined on C3 plants. Though, the study analysis reveals that he might have eaten aquatic foods like fresh water fish.

The bone’s genetic analysis revealed that the man was closely related to present-day Asians and to early Europeans. “From this we conclude that the population to which the Ust’-Ishim individual belonged diverged from the ancestors of present-day Europeans and Asians before, or at around the same time as, these groups diverged from one another,” Kelso said.

The Siberian man carried a similar level of Neanderthal ancestry as present-day Eurasians and the Neanderthal genes moved into the ancestors of this man 7,000 to 13,000 years before he lived, researchers revealed.

The results of the study propose that modern humans and Neanderthals mated around 50,000 to 60,000 years ago, “which is close to the time of the major expansion of modern humans out of Africa and the Middle East,” Kelso said.

The study is published in the Nature journal.

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